h = actxserver('progid') creates a local OLE Automation server, where progid is the programmatic identifier of an OLE-compliant COM server, and h is the handle of the server's default interface.
Get progid from the control or server vendor's documentation. To see the progid values for MATLAB® software, refer to Programmatic Identifiers. https://www.mathworks.com/help/matlab/matlab_external/introduction_brd0vd4-1.html#bq54l7x-1
Chrome is not OLE COM compliant and hence does have an associated PROGID that can be used to controll it via ActXServer.
Most likely Safari does not have one either, since COM is a Windows technology and Safari has strong ties to Mac.