how make clear or decrease below image from contaminated pixels? I indicated some of them

I want to extracted blood vessels far from those contaminated pixels

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Not sure what that means. It looks like the blood vessels are already enhanced. Do you have a binary image specifying what pixels are in or out of your red regions?

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Preguntada:

el 12 de Oct. de 2019

Cerrada:

el 20 de Ag. de 2021

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