Bispecific Protein Degrader PK-PD Model for SimBiology

SimBiology project file for a published PK-PD model for bispecific protein degraders

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The SimBiology model described in the following publication:
Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z
Please note that some of the included visualizations require the "gridfit" routine written by John D'Errico: Surface Fitting using gridfit (https://www.mathworks.com/matlabcentral/fileexchange/8998-surface-fitting-using-gridfit), MATLAB Central File Exchange.

Citar como

Bartlett DW, Gilbert AM. A kinetic proofreading model for bispecific protein degraders. J Pharmacokinet Pharmacodyn. 2021;48(1):149-163. doi:10.1007/s10928-020-09722-z

Información general

Compatibilidad con la versión de MATLAB

  • Compatible con cualquier versión desde R2022a

Compatibilidad con las plataformas

  • Windows
  • macOS
  • Linux
Comunidades de usuarios
Versión Publicado Notas de la versión Action
1.0.2

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.

1.0.1

Modified for compatibility with SimBiology R2022a and newer. The initial release version 1.0.0 was created with SimBiology R2018b and will give errors in the custom visualization programs when run in newer versions of SimBiology.

1.0.0