How to make relationship between some factor images to a some subset of images in matlab using ANN

I am a beginner of Matlab. I am trying to establish a non linear relationship(ANN) between some training images and some factors that affects those training images.In details,

1. I have a raster layer with only two values, 0 means no forest degradation and 1 means forest degradation
2. Several other raster layers- distance to road, distance to market centers(where wood is sold), elevation raster layer etc for all layers all the values normalized in a scale of 0-1
3. I divided the whole of the layer 1 into square blocks, from those blocks I randomly took(training samples) some block(subset of image).

Keep in mind that layers 2 affects the layer 1(forest degradation).

Now I want to create a relationship between those factors in layer 2 and layer 3- based on this relationship I want to predict the value of layer 1 in the non sample blocks. Means that for a place(not in the training sample area) based on the values of the layers got from step 2 I can predict the values(0 or 1) there provided that training.I am using Matlab 2016