How can I use the save function in matlab to save a variable in the workspace, which is actually a two dimensional table, into an existing .dat file from which I previously loaded that variable?

load ('datos22.dat', '-mat');

for i=1:2:43
    datos(:,i)=datos(:,i)+6;
end

save('datos.dat',datos,' -dat')

[Ramnarayan Krishnamurthy]

This answer may be useful if you are want to update an existing variable in the mat file:

https://www.mathworks.com/matlabcentral/answers/33113-append-save-same-variable-with-updated-values-into-mat-file-row-wise

[PeakyClimber]

Thank you but my problem is that I loaded a variable which is composed of of a 46x43 data table from a.dat file, using "load" function with -mat extension. Afterwards I made some changes in such variable table (the "for" function you see above), and then what I want is to overwrite the firstly used .dat file with the modified values and save. There must be something that can be done, my teacher is asking for it.