How to create custom error model in Simbiology

Hello. I am doing population pharmacokinetic analysis using Simbiology. There are 4 types of error model available in Simbiology. Constant (y = f+a*e), exponential (y = exp(a*e)), combined (y = f + (a+b*f)*e) and proporttional (y = f+b*f*e).

Suppose i want to create new error model say

y = f * (1+a)+b

How will I be able to achieve it.

Regards.

Answer 1

[Jeremy Huard]

Hi Praveen,

the error model you suggested looks like a combined error model. But from your equation I don't see whether you expect one or two normally distributed random variable(s). How does the error term look like?

If it is (a+b*|f|)*e, then it's exactly SimBiology's combined error model.

If it is (a*e1 + b*|f|*e2), then unfortunately it can't be implemented in SimBiology as SimBiology does not support custom error models as of release R2019a.

Best,

Jérémy

[Praveen Kumar M]

Thanks Jeremy for the clarification. I suppose that I can proceed forward with combined error model as suggested.